ARTICLE ORegan_FRONTIERSINDIGITALHEALTH_2025/IDIAP UpSMART: five years of digital innovation in cancer clinical research---achievements, challenges, and recommendations O'Regan, Paul Butt, Fouziah Carter, Louise Graham, Donna M. Le Blanc, Anja Hoskins, Richard Stephenson, Laura Patil, Akshita Shabbir, Muhammad Eken, Dilan Singh, Subir Villa, Andrea Agnelli, Luca Damian, Silvia Grave, Christopher Pretelli, Giulia Garralda, Elena Frost, Hannah de Braud, Filippo Freitas, Andre Dive, Caroline Unsworth, Harriet Frontiers in Digital Health 7 2025 10.3389/fdgth.2025.1708067 doi